Obsessive-Compulsive Disorder (OCD) is a chronic and long-lasting disorder in which a
person has uncontrollable, recurrent thoughts (obsessions) and behaviours (compulsions)
that he or she feels the urge to repeat over and over1.
Two measures are the two most widely used :
pharmacological and psychological2.
Clomipramine was the first agent found to have efficacy in OCD .The drug has the pharmacological properties of the
tricyclic group of antidepressants 3.The antidepressant effects
of clomipramine are believed to be due to reuptake inhibition of serotonin and norepinephrine
while just serotonin reuptake inhibition
is believed to be cause for the efficacy
of clomipramine in the treatment of OCD4.
SSRIs are the first line drugs in treating OCD. The adverse reactions of
SSRIs are less, so improved compliance is observed. Available SSRIs
include fluoxetine, fluvoxamine , paroxetine , citalopram , escitalopram , and
Despite the proven
efficacy of SSRIs and clomipramine in OCD,
many patients show no or just slight symptom improvement to a medication.
The combination of the antipsychotics risperidone, haloperidol, olanzapine, or
quetiapine along with an SSRI was found
to be to be more efficacious than SSRI therapy in such cases and is suggested
by the WFSBP World Federation of Societies of
Prescribing a suitable
medication for a particular patient is done on the basis of many factors
including patient’s demographic characteristics, illness history, adverse
reactions of the medication, co morbidities. So, a study of prescribing
patterns can help in identifying current practices of the use of medications.7.
The concept of QOL is often considered a missing
measurement in healthcare. Knowledge
about QOL was found to be useful
because many studies showed correlations between QOL and distress that often
leads to worsening of symptoms such as
those of OCD. Hence, the main objectiveof the present study was to assess QOL in patients suffering from OCD8.
Today, in an age where health care is scrutinized, not
only for the quality of that which we provide but also the satisfaction of
those who receive it. So, it is
necessary to find out weaknesses in
health care systems for better patient