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MULTIPLE SCLEROSIS PATHOPHYSIOLOGY ASSESSMENTBy Faiq KamangarClassProfessorSchoolTown of schoolNovember 17, 2017Classification of the diseaseMultiple sclerosis (MS) is a chronic inflammatory autoimmune  disorder of the central nervous system (CNS) and is  the most common causes of nontraumatic disability among young and middle-aged adults.  There are four types of multiple sclerosis the most common is Clinically isolated Syndrome (CIS) , Secondary Progressive MS (SPMS), Relapsing-Remitting MS (RRMS), and Primary Progressive MS (PPMS).Mortality Rate Although there is no known cure for MS, it is not a fatal disease, patients have to contend with their quality of life being disrupted. Patients are more likely to die from respiratory failure, heart failure, pneumonia and sepsis. Multiple sclerosis is not listed as the main cause of death on most death certificates. The risk of suicide for MS patients has increased due to depression and patients not wanting to live with the pain.Signs of the MS Symptoms can vary from one patient to another no two patients are the same. The most common early signs and symptoms of multiple sclerosis are vision problems, fatigue, tingling and numbness, vertigo, dizziness, muscle weakness and spasm, problems with balance and coordination. Less common symptoms are speech and swallowing problems, cognitive dysfunction, difficulty walking, tremor, breathing problems,bladder and bowel dysfunction, Sexual dysfunction and mood swings and depression. If MS is not treated, more than 30% of patients will have severe physical disability after 20-25 years of onset. Many modifying agents used in MS treatments have slowed down the disability. The majority of people who have MS will experience a normal life span. On average, people with MS live about seven years less than the people without. People with rare types of MS may potentially affect their lifespan. The cause of multiple sclerosis is unknown. MS is considered an autoimmune disease in which the body’s immune system attacks its own tissues.” In the case of MS, this immune system malfunction destroys myelin (the fatty substance that coats and protects nerve fibers in the brain.” It isn’t clear why MS develops in some people and not others. Researchers believe that a combination of genetics and environmental factors appears to be responsible.These risk factors may increase your risk of developing Multiple Sclerosis.https://www.mayoclinic.org/diseases-conditions/multiple-sclerosis/symptoms-causes/syc-20350269Sex. Women are about twice as likely as men are to develop MSFamily history. If one of your parents or siblings has had MS, you are at higher risk of developing the disease.Certain infections. A variety of viruses have been linked to MS, including Epstein-Barr, the virus that causes infectious mononucleosis. Race. White people, particularly those of Northern European descent, are at highest risk of developing MS. People of Asian, African or Native American descent have the lowest risk. Climate. MS is far more common in countries with temperate climates, including Canada, the northern United States, New Zealand, southeastern Australia and Europe.Pathophysiology AssessmentEpidemiology of Multiple SclerosisMultiple Sclerosis affects 2.3 million people around the world. Although  (MS) can not be directly inherited and can not be transferred from person to person. Scientist have study patterns of MS and have found factors that may help them find the cause. “The factors are age, gender, genetics, ethnic background, and geography.”  (“Who Gets MS? (n.d.). Retrieved November 30, 2017, from https://www.nationalmssociety.org/What-is-MS/Who-Gets-MS “)MS is  considered an autoimmune disease in which the body’s immune system attacks its own tissues. In the case of MS, the immune system malfunction destroys myelin (the fatty substance that coats and protects nerve fibers in the brain and spinal cord). (“https://www.mayoclinic.org/diseases-conditions/multiple-sclerosis/symptoms-causes/syc-20350269”) In the United States there is about 400,000 people who have MS. world wide there are 2.5 million people with MS.  Everyday around 200 people are diagnosed with MS. There has not been an epidemic of  Multiple Sclerosis. (“https://www.healthline.com/health/multiple-sclerosis/facts-statistics-infographic”)

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